+AA2024-2025 Prof. Stefania Bortoluzzi - MOLECULAR METHODS AND BIOINFORMATICS, Master degree in Evolutionary Biology, School of Science, University of Padova

stones

A.A. 2024-2025

MOLECULAR METHODS AND BIOINFORMATICS
Master degree in Evolutionary Biology, School of Science, University of Padova

Teachers: Prof. STEFANIA BORTOLUZZI, Prof. GIANLUCA OCCHI

Info sul corso

Ist semester course valid for 11 University training credits (CFU), with 56 teaching hours (7 CFU) and 64 hours of laboratory/practical activities (4 CFU), both split in the two parts.

Course presentation

Program and materials of the course

PART OF BIOINFORMATICS

Teacher: Prof. STEFANIA BORTOLUZZI

Collaborators: Dr. Enrico Gaffo, Dr. Silvia Orsi

LECTURES MATERIALS
Introduction to the course
Slides
Database and data retrieval (biosequences, secondary databases, knowledgegebases, molecular structures).
Slides
Sequence alignment, scoring matrices, exact and euristico methods. Similarity search and BLAST. Slides
Slides
Multiple sequence alignment: from classic progressive methods to recent advances.
Slides
Molecular structure prediction. Protein and RNA folding. Fold predizione approaches (ab inizio, comparative modeling and threading). Neural networks.
Slides
Genome sequencing and annotation. Genomic databases. Second and third generation methods for massive DNA sequencing (NGS). Genome sequencing (de novo) e resequencing. Introduction to NGS data analysis. Slides
RNA-seq: transcriptome sequencing and analysis in model and non-model species Slides
PRACTICAL SESSIONS MATERIALS
I Bioinformatics practical session Guide
II Bioinformatics practical session Guide
III Bioinformatics practical session Guide
IV Bioinformatics practical session Guide
V Bioinformatics practical session Guide
VI Bioinformatics practical session Guide
VII Bioinformatics practical session Guide

PARTE COMUNE

JOURNAL CLUB MATERIALS
Tuesday 3 and 10 December 2024
FORM for the JC organization (Student groups, dates, rules and selected papers)

Contact of the referent teacher

Stefania Bortoluzzi <stefania.bortoluzzi@unipd.it>