{"id":64,"date":"2015-08-27T11:29:21","date_gmt":"2015-08-27T09:29:21","guid":{"rendered":"http:\/\/compgen.bio.unipd.it\/~enrico\/?page_id=64"},"modified":"2022-11-17T16:15:01","modified_gmt":"2022-11-17T15:15:01","slug":"about","status":"publish","type":"page","link":"https:\/\/compgen.bio.unipd.it\/~enrico\/index.php\/about\/","title":{"rendered":"About"},"content":{"rendered":"

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Academic Background:<\/strong><\/em>
- PhD in Bioscience and Biotechnology - Genetics and Molecular Biology of the Development
- Master's Degree in Computer Science - Bioinformatics. University of Trento, Italy
- Bachelor's Degree in Computer Science. University of Padova, Italy<\/span><\/p>\n

Research Grants:<\/strong><\/em><\/p>\n

- 2022 - 2023:\u00a0Post-doc fellowship at the Department of Medicine, University of Padova, Italy. Project: Study of circular RNAs in B-cell lymphoproliferative diseases<\/p>\n

- 2021 - 2022: Post-doc fellowship at the Department of Molecular Medicine, University of Padova, Italy. Project: Study of circular RNA in normal hematopoiesis and leukemias.<\/p>\n

-\u00a02020 - 2021: Awarded with Post-doctoral Fellowship 2020 Fondazione Umberto Veronesi. Project: Characterization of small RNAs in plasmatic exosomes of Hodgkin and anaplastic large cell lymphoma pediatric patients from EuroNet-PHL-C2 and ALCL99 trials. Host institution: Department of Molecular Medicine, University of Padova, Italy.<\/p>\n

-\u00a02019 - 2020: Awarded with Post-doctoral Fellowship 2019 Fondazione U. Veronesi. Project: RNA-seq analysis of exosomal small RNAs to identify disease biomarkers of pediatric Hodgkin and non-Hodgkin lymphomas treated according to ALCL99 and EuroNet-PHL-C2 trials. Host institution: Department of Molecular Medicine, University of Padova, Italy.<\/p>\n

-\u00a02017 - 2019: Post-doc fellowship at the Department of Women\u2019s and Children\u2019s Health, University of Padova, Italy. Project: Molecular characterization of DNA\/RNA of primary tumor in pediatric patients afflicted with rhabdomyosarcoma using NGS techniques, extensive bioinformatic analysis, genomic data processing and in particular NGS data.<\/p>\n

-\u00a02016 - 2017: Post-doc fellowship at the Department of Molecular Medicine, University of Padova, Italy. Project: Development and application of bioinformatics methods for the study of transcriptome in tumors.<\/p>\n

-\u00a02014 - 2015: Fellowship at the Department of Biology, University of Padova, Italy. Project: Development and application of computational methods for the integrative study of transcriptome using RNA-seq.<\/p>\n

- 2012 - 2013: Fellowship at the Department of Science and Agricultural Technology, University of Bologna. Project: Swine fat tissue transcriptome analysis.<\/p>\n

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<\/span>\"cv\"<\/p>\n<\/div><\/div><\/div><\/div>

<\/span>\"publications\"<\/p>\n<\/div><\/div><\/div>

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Articles in scientific journals<\/strong><\/em>
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Check my Google Scholar profile here<\/a> for the complete and updated list of my publications.<\/p>\n

- Buratin A., Bortoluzzi S., Gaffo E. Systematic benchmarking of statistical methods to assess differential expression of circular RNAs. In Review. Preprint at https:\/\/www.researchsquare.com\/article\/rs-2018316<\/a><\/p>\n

- Buratin A, Borin C, Tretti Parenzan C, Dal Molin A, Orsi S, Binatti A, Simon K, Paganin M, Serafin V, Gaffo E, et al. CircFBXW7 in patients with T-cell ALL: depletion sustains MYC and NOTCH activation and leukemia cell viability. In Review<\/p>\n

- Dal Molin A., Tretti Parenzan C., Gaffo E., et al. Discovery of fusion circular RNAs in leukemia with KMT2A::AFF1 rearrangements by the new software CircFusion. In Review<\/p>\n

-\u00a0Damanti C. C., Ferrone L., Gaffo E., et al. Plasma small-extracellular vesicles enriched in miR-122-5p promote disease aggressiveness in pediatric Anaplastic Large Cell Lymphoma. In Review<\/p>\n

-\u00a0Buratin A, Romualdi C, Bortoluzzi S, and Gaffo E*. Detecting differentially expressed circular RNAs from multiple quantification methods using a generalized linear mixed model. Computational and Structural Biotechnology Journal<\/strong> 2022. 20, 2495\u20132502. doi: 10.1016\/j.csbj.2022.05.026. *corresponding author<\/p>\n

-\u00a0Dal Molin A, Gaffo E, Difilippo V, Buratin A, Tretti Parenzan C, Bresolin S, and Bortoluzzi S. CRAFT: a bioinformatics software for custom prediction of circular RNA functions. Brief Bioinform<\/strong>. 2022. 23, bbab601. doi: 10.1093\/bib\/bbab601.<\/p>\n

-\u00a0Gaffo E*, Buratin A, Dal Molin A, and Bortoluzzi S*. Sensitive, reliable and robust circRNA detection from RNA-seq with CirComPara2. Brief Bioinform<\/strong>. 2022, 23, bbab418. doi: 10.1093\/bib\/bbab418. *corresponding authors<\/p>\n

-\u00a0Buratin A, Gaffo E, Dal Molin A, Bortoluzzi S. CircIMPACT: An R Package to Explore Circular RNA Impact on Gene Expression and Pathways. Genes<\/strong>. 2021. p. 1044. doi:10.3390\/genes12071044<\/p>\n

-\u00a0Boldrin E, Gaffo E, Niedermayer A, Boer JM, Zimmermann M, Weichenhan D, et al. MicroRNA-497\/195 is tumor-suppressive and cooperates with CDKN2A\/B in pediatric acute lymphoblastic leukemia. Blood<\/strong>. 2021. doi:10.1182\/blood.2020007591<\/p>\n

-\u00a0Di Battista P, Lovisa F, Gaffo E, Gallingani I, Damanti CC, Garbin A, et al. Low miR-214-5p Expression Correlates With Aggressive Subtypes of Pediatric ALCL With Non-Common Histology. Front Oncol<\/strong>. 2021;11: 663221.<\/p>\n

-\u00a0Damanti CC*, Gaffo E*, Lovisa F, Garbin A, Di Battista P, Gallingani I, et al. MiR-26a-5p as reference to normalize microRNA qRT-PCR levels in plasmatic exosomes of pediatric hematologic malignancies. Cells<\/strong>. 2021; 10(1), 101. doi: 10.3390\/cells10010101. *first authors.<\/p>\n

-\u00a0Lovisa F, Garbin A, Crotti A, Di Battista P, Gallingani I, Damanti CC, Tosato A, Carraro E, Pillon M, Mafakheri E, Romanato F, Gaffo E, Biffi A, Bortoluzzi S, Agostini M, Mussolin L. Increased tenascin C, osteopontin and HSP90 levels in plasmatic exosomes of pediatric ALK-positive anaplastic large cell lymphoma: new diagnostic opportunity? Diagnostics<\/strong>. 2021; 11(2), 253. doi: 10.3390\/diagnostics11020253<\/p>\n

-\u00a0Dal Molin A, Hofmans M, Gaffo E, Buratin A, Cav\u00e9 H, Flotho C, et al. CircRNAs Dysregulated in Juvenile Myelomonocytic Leukemia: CircMCTP1 Stands Out. Frontiers in Cell and Developmental Biology<\/strong>. 2020 doi: 10.3389\/fcell.2020.613540<\/p>\n

-\u00a0Buratin A, Paganin M, Gaffo E, Dal Molin A, Roels J, Germano G, et al. Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes. Blood Advances<\/strong>. 2020; 4 (23): 5902\u20135914. doi: 10.1182\/bloodadvances.2020002337<\/p>\n

-\u00a0Lovisa F, Di Battista P, Gaffo E, Damanti CC, Garbin A, Gallingani I, et al. RNY4 in Circulating Exosomes of Patients With Pediatric Anaplastic Large Cell Lymphoma: An Active Player? Frontiers in Oncology<\/strong>. 2020. doi:10.3389\/fonc.2020.00238<\/p>\n

-\u00a0Gaffo E, Bortolomeazzi M, Bisognin A, Di Battista P, Lovisa F, Mussolin L, et al. MiR&moRe2: A Bioinformatics Tool to Characterize microRNAs and microRNA-Offset RNAs from Small RNA-Seq Data. Int J Mol Sci<\/strong>. 2020;21. doi:10.3390\/ijms21051754<\/p>\n

-\u00a0Bortolomeazzi M, Gaffo E*, Bortoluzzi S*. A survey of software tools for microRNA discovery and characterization using RNA-seq. Brief Bioinform<\/strong>. 2019;20: 918\u2013930. *corresponding authors<\/p>\n

-\u00a0Molin AD, Bresolin S, Gaffo E, Tretti C, Boldrin E, Meyer LH, et al. CircRNAs Are Here to Stay: A Perspective on the MLL Recombinome. Frontiers in Genetics<\/strong>. 2019. doi:10.3389\/fgene.2019.00088<\/p>\n

-\u00a0Agnelli L, Bisognin A, Todoerti K, Manzoni M, Taiana E, Galletti S, Gaffo E, et al. Expanding the repertoire of miRNAs and miRNA-offset RNAs expressed in multiple myeloma by small RNA deep sequencing. Blood Cancer J<\/strong>. 2019;9: 21.<\/p>\n

-\u00a0Gaffo E, Boldrin E, Dal Molin A, Bresolin S, Bonizzato A, Trentin L, et al. Circular RNA differential expression in blood cell populations and exploration of circRNA deregulation in pediatric acute lymphoblastic leukemia. Sci Rep<\/strong>. 2019;9: 14670.<\/p>\n

-\u00a0Davoli R*, Gaffo E*, Zappaterra M, Bortoluzzi S, Zambonelli P. Identification of differentially expressed small RNAs and prediction of target genes in Italian Large White pigs with divergent backfat deposition. Anim Genet<\/strong>. 2018;49: 205\u2013214. *first authors<\/p>\n

-\u00a0Gaffo E, Bonizzato A, Kronnie G, Bortoluzzi S. CirComPara: A Multi\u2010Method Comparative Bioinformatics Pipeline to Detect and Study circRNAs from RNA\u2010seq Data. Non-Coding RNA<\/strong>. 2017. p. 8. doi:10.3390\/ncrna3010008<\/p>\n

-\u00a0Bortoluzzi S, Lovisa F, Gaffo E, Mussolin L. Small RNAs in Circulating Exosomes of Cancer Patients: A Minireview. High Throughput<\/strong>. 2017;6. doi:10.3390\/ht6040013<\/p>\n

-\u00a0Bonizzato, A., Gaffo, E., te Kronnie, G., and Bortoluzzi, S. (2016). CircRNAs in hematopoiesis and hematological malignancies. Blood Cancer Journal<\/strong> 6, e483.<\/p>\n

-\u00a0Calura, E., Pizzini, S., Bisognin, A., Coppe, A., Sales, G., Gaffo, E., Fanelli, T., Mannarelli, C., Zini, R., Norfo, R., et al. (2016). A data-driven network model of primary myelofibrosis: transcriptional and post-transcriptional alterations in CD34+ cells. Blood Cancer Journal<\/strong> 6, e439.<\/p>\n

-\u00a0Zambonelli P*, Gaffo E*, Zappaterra M, Bortoluzzi S, Davoli R. Transcriptional profiling of subcutaneous adipose tissue in Italian Large White pigs divergent for backfat thickness. Animal Genetics<\/strong>. 2016. pp. 306\u2013323. doi:10.1111\/age.12413 * first authors<\/p>\n

-\u00a0Gaffo, E., Zambonelli, P., Bisognin, A., Bortoluzzi, S. and Davoli, R. (2014), \u201cmiRNome of\u00a0Italian Large White pig subcutaneous fat tissue: new miRNAs, isomiRs and moRNAs\u201d. Animal\u00a0Genetics<\/strong>. doi: 10.1111\/age.12192<\/p>\n<\/div><\/div><\/div><\/div><\/div>

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My projects<\/strong><\/em><\/span><\/p>\n

Check my projects in GitHub:\u00a0http:\/\/github.com\/egaffo<\/a><\/p>\n

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Academic Background: – PhD in Bioscience and Biotechnology – Genetics and Molecular Biology of the Development – Master’s Degree in Computer Science – Bioinformatics. University of Trento, Italy – Bachelor’s Degree in Computer Science. University of Padova, Italy Research Grants: – 2022 – 2023:\u00a0Post-doc fellowship at the Department of Medicine, University of Padova, Italy. Project: Read More …<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"full-width-page.php","meta":{"footnotes":""},"class_list":["post-64","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/compgen.bio.unipd.it\/~enrico\/index.php\/wp-json\/wp\/v2\/pages\/64","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/compgen.bio.unipd.it\/~enrico\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/compgen.bio.unipd.it\/~enrico\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/compgen.bio.unipd.it\/~enrico\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/compgen.bio.unipd.it\/~enrico\/index.php\/wp-json\/wp\/v2\/comments?post=64"}],"version-history":[{"count":24,"href":"https:\/\/compgen.bio.unipd.it\/~enrico\/index.php\/wp-json\/wp\/v2\/pages\/64\/revisions"}],"predecessor-version":[{"id":81,"href":"https:\/\/compgen.bio.unipd.it\/~enrico\/index.php\/wp-json\/wp\/v2\/pages\/64\/revisions\/81"}],"wp:attachment":[{"href":"https:\/\/compgen.bio.unipd.it\/~enrico\/index.php\/wp-json\/wp\/v2\/media?parent=64"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}