Alessandro Coppe

Bioinformatics Assistant Professor at University of Padua

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I'm a bioinformatician analyzing human cancer genomics, with the goal to discover and interpretate the effect of tumor driver/germline mutations. I'm currently using whole-exome or whole-genome data produced by Next-Generation Sequencing (NGS) technologies.



Specialities:

  • Next-generation sequencing data analysis and pipelines development.
  • Strong programming skills (Python, R/bioconductor among others).
  • Large scale genomic and biomedic data integration.
  • Cancer genomics.
  • Data and knowledge integration for biological hypothesis generation.

Last publications:

  1. Lovisa F, Binatti A, Coppe A, Primerano S, Carraro E, Pillon M, Pizzi M, Guzzardo V, Buffardi S, Porta F, Farruggia P, De Santis R, Bulian P, Basso G, Lazzari E, d'Amore ESG, Bortoluzzi S, Mussolin L. A high definition picture of key genes and pathways mutated in pediatric follicular lymphoma. . Haematologica. 2019 Feb 18. doi: 10.3324/haematol.2018.211631. PMID: 30819919.
  2. Esposito MR, Binatti A, Pantile M, Coppe A, Mazzocco K, Longo L, Capasso M, Lasorsa VA, Luksch R, Bortoluzzi S, Tonini GP. Somatic mutations in specific and connected subpathways are associated with short neuroblastoma patients' survival and indicate proteins targetable at onset of disease. Int J Cancer. 2018 Jul 11. doi: 10.1002/ijc.31748. [Epub ahead of print] PubMed PMID: 29992558.
  3. Salvoro C, Bortoluzzi S, Coppe A, Valle G, Feltrin E, Mostacciuolo ML, Vazza G. Rare Risk Variants Identification by Identity-by-Descent Mapping and Whole-Exome Sequencing Implicates Neuronal Development Pathways in Schizophrenia and Bipolar Disorder. Mol Neurobiol. 2018 Sep;55(9):7366-7376. doi: 10.1007/s12035-018-0922-2. Epub 2018 Feb 6. PubMed PMID: 29411265.
  4. Coppe A, Nogara L, Pizzuto MS, Cani A, Cesaro S, Masetti R, Locatelli F, Te Kronnie G, Basso G, Bortoluzzi S, Bresolin S. Somatic mutations activating Wiskott-Aldrich syndrome protein concomitant with RAS pathway mutations in juvenile myelomonocytic leukemia patients. Hum Mutat. 2018 Apr;39(4):579-587u doi: 10.1002/humu.23399. Epub 2018 Jan 19. PubMed PMID: 29316027.
  5. Coppe A, Andersson EI, Binatti A, Gasparini VR, Bortoluzzi S, Clemente M, Herling M, Maciejewski J, Mustjoki S, Bortoluzzi S. Genomic landscape characterization of large granular lymphocyte leukemia with a systems genetics approach. Leukemia. 2017 May;31(5):1243-1246. doi: 10.1038/leu.2017.49. Epub 2017 Feb 7. PubMed PMID: 28167832; PubMed Central PMCID: PMC5419584.

Location:

You can find me at fourth floor, south side, Viale G. Colombo 3 (pedestrian access) Via U.Bassi 58/B (by car) 35131 Padova, Italy.